Smoked Turkey Grilled Cheese

Featured in: Smoky Sandwiches & Burgers

This savory smoked turkey and sharp cheddar sandwich features a tangy cranberry-mustard spread that adds sweet and savory depth. Buttered bread is grilled until golden and crispy on the outside while the cheese melts perfectly inside, creating a delicious contrast of textures. Simple enough for a quick lunch yet impressive enough for entertaining, this sandwich comes together in just 18 minutes.

Updated on Sun, 18 Jan 2026 12:27:00 GMT
A close-up of a golden-brown Smoked Turkey Grilled Cheese, oozing with sharp cheddar and tangy cranberry spread on sourdough bread. Save
A close-up of a golden-brown Smoked Turkey Grilled Cheese, oozing with sharp cheddar and tangy cranberry spread on sourdough bread. | grilto.com

I was standing in front of the fridge the day after Thanksgiving, staring at leftovers I didn't want to reheat in the microwave again. The smoked turkey was still moist, the cranberry sauce sat untouched, and I had a block of sharp cheddar that needed using. I buttered two slices of sourdough and built what turned into the best post-holiday sandwich I've ever made. That first bite, with the cheese pulling and the cranberry cutting through the richness, made me wonder why I'd never thought of it before.

My neighbor knocked on the door one Saturday afternoon, and I was mid-sandwich when I answered. She asked what smelled so good, and I ended up making her one on the spot. We stood in the kitchen eating them over the sink, cheese dripping onto our hands, laughing about how something so simple could feel like such a discovery. She still texts me every November asking if I'm making "that sandwich" again.

Ingredients

  • Hearty sandwich bread: Sourdough holds up to the butter and doesn't get soggy, and its tang plays well with the cranberry, though whole wheat adds a nutty depth if that's your preference.
  • Smoked turkey breast: The smokiness is key here, it adds a layer deli turkey alone can't match, so look for real smoked turkey at the deli counter or use quality leftovers.
  • Sharp cheddar cheese: Sharp cheddar has the bite to stand up to the sweetness of the cranberry without disappearing into the background.
  • Cranberry sauce: Whole berry gives texture, jellied gives smoothness, either works as long as it's good quality and not too sugary.
  • Dijon mustard: Just a teaspoon cuts the sweetness and adds a subtle heat that makes the whole thing more complex.
  • Unsalted butter: Softened butter spreads easily and crisps the bread evenly without burning, salted butter can make the outside too salty.

Instructions

Make the cranberry spread:
Stir the cranberry sauce and Dijon together in a small bowl until they're fully combined and smooth. This takes about 30 seconds and makes spreading so much easier than dolloping cranberry straight onto bread.
Butter the bread:
Lay out all four slices and spread softened butter on one side of each, making sure to go all the way to the edges so every bite gets crispy. Flip them over so the buttered sides are facing down.
Assemble the sandwiches:
Spread the cranberry mixture evenly on two slices, then layer the turkey and cheese on top, making sure the cheese touches the bread so it melts properly. Cap each with the remaining slices, buttered side up.
Grill until golden:
Heat your skillet over medium heat and place both sandwiches in once it's warm, pressing gently with a spatula. Cook for 3 to 4 minutes per side until the bread turns deep golden and the cheese has melted into the turkey.
Rest and serve:
Let the sandwiches sit for a full minute after pulling them from the pan so the cheese sets slightly and doesn't all run out when you cut. Slice in half and serve while still warm.
Smoked Turkey Grilled Cheese cut diagonally, revealing layers of savory smoked turkey and melted sharp cheddar inside the toasted sandwich. Save
Smoked Turkey Grilled Cheese cut diagonally, revealing layers of savory smoked turkey and melted sharp cheddar inside the toasted sandwich. | grilto.com

I made these for my kids one rainy Sunday when we were all a little stir-crazy and needed something cozy. They didn't think they'd like cranberry sauce on a sandwich, but they both went quiet after the first bite, which is how I know something's good. Now it's become our unofficial comfort lunch when the weather turns cold and we need something that feels like a hug.

Choosing Your Bread

The bread is more important than you'd think because it has to support the fillings without falling apart or getting soggy. Sourdough is my favorite for its structure and flavor, but a good whole wheat or even a seeded multigrain works beautifully if you want something heartier. Avoid anything too soft or fluffy, it won't crisp properly and tends to compress into nothing under the weight of the fillings.

Cheese Variations That Work

Sharp cheddar is classic, but I've also had great results with Gruyère when I want something a little more sophisticated, and smoked Gouda when I want to double down on the smokiness of the turkey. Swiss is mild and melts like a dream, though it won't give you as much flavor punch. Whatever you choose, make sure it's a good melting cheese and slice or shred it yourself for the best texture.

Serving and Pairing Ideas

This sandwich is rich enough to be a full meal on its own, but it pairs beautifully with something crisp and light on the side. A simple green salad with a tart vinaigrette cuts through the richness, or you can go for roasted sweet potato fries if you want something a little more substantial. I've also served it with a cup of tomato soup for dipping, which feels nostalgic and perfect on a cold afternoon.

  • Add a handful of fresh arugula or baby spinach inside the sandwich for a peppery crunch.
  • Serve with pickles or pickled onions on the side to balance the sweetness.
  • Pair with a crisp apple cider or a light lager if you're making it for a casual lunch with friends.
Sizzling Smoked Turkey Grilled Cheese cooking in a skillet, with buttered sourdough slices crisping to a perfect golden brown. Save
Sizzling Smoked Turkey Grilled Cheese cooking in a skillet, with buttered sourdough slices crisping to a perfect golden brown. | grilto.com

This sandwich has become one of those recipes I reach for when I need something fast, satisfying, and just a little bit special without any fuss. I hope it becomes that for you too.

Recipe Help & Answers

Can I prepare the cranberry spread ahead of time?

Yes, you can mix the cranberry sauce and Dijon mustard up to one day in advance. Store it in an airtight container in the refrigerator until ready to use.

What bread works best for this sandwich?

Sourdough and whole wheat are excellent choices due to their sturdy structure that holds up well to butter and grilling. Brioche or challah offer a softer, more indulgent option.

How do I prevent the cheese from leaking out?

Layer the cheese between the turkey and bread slices, and press gently while cooking rather than firmly. This keeps the filling contained and allows the cheese to melt gradually.

What cheese alternatives work well?

Swiss cheese, Gruyère, and smoked Gouda all pair beautifully with smoked turkey. Each brings unique flavors—Swiss is mild and nutty, Gruyère is creamy and complex, and smoked Gouda adds additional smokiness.

Can I add vegetables to this sandwich?

Absolutely. Baby spinach, arugula, thinly sliced tomato, or caramelized onions complement the smoky turkey and cranberry spread perfectly. Add vegetables before closing the sandwich.

What should I serve alongside this sandwich?

A light green salad, sweet potato fries, or soup make great pairings. The tangy cranberry and rich cheese pair well with acidic vinaigrettes or creamy bisques.

Smoked Turkey Grilled Cheese

Savory smoked turkey and cheddar sandwich with cranberry spread, melted together on golden toasted bread.

Prep Time
10 min
Time to Cook
8 min
Complete Time
18 min
From grilto Jake Turner


Skill Level Easy

Cuisine Style American

Serves 2 Portions

Diet Details None specified

What You Need

Sandwich

01 4 slices hearty sandwich bread, sourdough or whole wheat
02 4 oz smoked turkey breast, thinly sliced
03 4 oz sharp cheddar cheese, sliced or shredded

Cranberry Spread

01 3 tablespoons cranberry sauce, whole berry or jellied
02 1 teaspoon Dijon mustard

For Grilling

01 2 tablespoons unsalted butter, softened

How-To

Step 01

Prepare Cranberry Spread: In a small bowl, combine cranberry sauce and Dijon mustard, mixing until well incorporated.

Step 02

Butter the Bread: Lay out all bread slices and spread a thin layer of butter on one side of each slice. Place buttered sides down on your work surface.

Step 03

Assemble Base Layer: Spread cranberry mixture evenly on the unbuttered side of two bread slices.

Step 04

Layer Fillings: Top the cranberry spread with smoked turkey slices and sharp cheddar cheese on each prepared bread slice.

Step 05

Complete Sandwich: Place remaining bread slices on top of each sandwich with buttered side facing outward.

Step 06

Heat Cooking Surface: Heat a large skillet or griddle over medium heat until evenly warmed.

Step 07

Cook Sandwiches: Place sandwiches in the skillet and cook for 3 to 4 minutes per side, pressing gently with a spatula, until bread achieves golden brown color and cheese melts completely.

Step 08

Rest and Serve: Remove sandwiches from pan and let rest for 1 minute. Slice diagonally and serve warm.

Essentials

  • Large skillet or griddle
  • Spatula
  • Small mixing bowl
  • Bread knife

Allergy Advisory

Review every component for allergens. Reach out to a health pro if you’re concerned.
  • Contains gluten from bread
  • Contains dairy from butter and cheese
  • May contain mustard
  • Contains poultry from turkey

Nutrition Details (per portion)

Facts listed here are for your info, not medical advice. Always double-check if needed.
  • Energy: 420
  • Lipids: 20 g
  • Carbohydrates: 36 g
  • Proteins: 24 g