Zesty Cajun Garlic Chicken

Featured in: One-Pan Meals

This vibrant dish combines tender chicken pieces and cheesy tortellini coated in a creamy Cajun garlic Parmesan sauce. Aromatics like garlic, onion, and bell pepper create a flavorful base, while Cajun seasoning and smoked paprika add a spicy kick. After sautéing chicken and vegetables, the sauce is simmered with heavy cream and Parmesan until smooth. Everything is gently tossed together and finished with fresh parsley for a quick, satisfying meal perfect for weeknights.

Updated on Sat, 15 Nov 2025 08:55:00 GMT
Creamy Zesty Cajun Garlic Parmesan Chicken Tortellini topped with fresh parsley, a delicious and easy weeknight dinner. Save
Creamy Zesty Cajun Garlic Parmesan Chicken Tortellini topped with fresh parsley, a delicious and easy weeknight dinner. | grilto.com

A vibrant and flavorful pasta dish featuring tender chicken, cheesy tortellini, and a creamy Cajun garlic Parmesan sauce. Perfect for a quick weeknight meal with a spicy kick.

The first time I made this Cajun Garlic Parmesan Chicken Tortellini, my family devoured it in minutes. The blend of creamy sauce and zesty Cajun spices makes every bite irresistible.

Ingredients

  • Chicken breasts: 2 large, boneless and skinless, cut into bite-sized pieces
  • Cheese tortellini: 500 g (18 oz) refrigerated
  • Garlic: 3 cloves, minced
  • Red bell pepper: 1 small, diced
  • Yellow onion: 1 small, diced
  • Heavy cream: 1 cup (240 ml)
  • Parmesan cheese: 1/2 cup (50 g) freshly grated
  • Unsalted butter: 2 tablespoons
  • Cajun seasoning: 1 tablespoon
  • Smoked paprika: 1/2 teaspoon
  • Black pepper: 1/2 teaspoon
  • Salt: 1/2 teaspoon, plus more to taste
  • Olive oil: 2 tablespoons
  • Fresh parsley: 2 tablespoons chopped, for garnish
  • Optional: Extra grated Parmesan for serving

Instructions

Cook tortellini:
Bring a large pot of salted water to a boil. Cook tortellini according to package instructions. Drain and set aside.
Cook chicken:
Heat 1 tablespoon olive oil in a large skillet over medium-high heat. Add chicken pieces, season with half the Cajun seasoning, salt, and pepper. Sauté until browned and cooked through, about 5-7 minutes. Remove chicken from skillet and set aside.
Sauté vegetables:
In the same skillet, add remaining olive oil and butter. Sauté onion and bell pepper for 3-4 minutes until softened. Add garlic and cook for 30 seconds until fragrant.
Build sauce:
Sprinkle in remaining Cajun seasoning and smoked paprika. Stir, then pour in the heavy cream. Bring to a gentle simmer, stirring frequently.
Add Parmesan:
Add Parmesan cheese and stir until melted and sauce is smooth. Taste and adjust seasoning if needed.
Combine chicken and pasta:
Return chicken to the skillet, along with cooked tortellini. Toss gently to coat everything in the sauce.
Finish and serve:
Cook for an additional 2-3 minutes until heated through. Serve garnished with fresh parsley and extra Parmesan if desired.
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| grilto.com

Gathering around the table to enjoy this creamy, spicy pasta always sparks smiles and laughter. It has quickly become a requested favorite for cozy family dinners.

Serving Suggestions

This dish pairs well with crusty bread to soak up the creamy sauce and a side salad dressed in a tangy vinaigrette for balance.

Ingredient Swaps

Swap chicken for shrimp to make a seafood version or choose spinach tortellini for an extra pop of color and flavor.

Storage & Leftovers

Store leftovers in an airtight container in the refrigerator for up to 3 days. Reheat gently on the stovetop, adding a splash of cream if the sauce thickens too much.

Close-up of golden Zesty Cajun Garlic Parmesan Chicken Tortellini with visible pieces of chicken and pasta. Save
Close-up of golden Zesty Cajun Garlic Parmesan Chicken Tortellini with visible pieces of chicken and pasta. | grilto.com

Finish with extra fresh parsley and Parmesan for a pop of color and flavor. Enjoy your zesty Cajun pasta adventure!

Recipe Help & Answers

What pasta works best with this dish?

Cheese tortellini is ideal as it pairs well with the creamy Cajun garlic Parmesan sauce, adding a cheesy texture that complements the chicken.

Can I adjust the spice level?

Yes, adding cayenne pepper or red pepper flakes increases heat, while reducing Cajun seasoning makes it milder.

Is there a seafood alternative?

Shrimp can replace chicken for a seafood variation that still works well with the creamy sauce.

How do I thicken the sauce if needed?

Simmer the sauce gently to reduce liquid or add a small amount of grated Parmesan to help thicken it naturally.

What sides complement this dish?

Crusty bread is great for soaking up sauce, and a crisp white wine like Sauvignon Blanc pairs nicely with the flavors.

Zesty Cajun Garlic Chicken

Tender chicken and cheesy tortellini in a creamy spicy garlic Parmesan sauce with fresh parsley garnish.

Prep Time
15 min
Time to Cook
25 min
Complete Time
40 min
From grilto Jake Turner


Skill Level Easy

Cuisine Style American/Italian Fusion

Serves 4 Portions

Diet Details None specified

What You Need

Proteins

01 2 large boneless, skinless chicken breasts, cut into bite-sized pieces

Pasta

01 18 oz refrigerated cheese tortellini

Vegetables & Aromatics

01 3 cloves garlic, minced
02 1 small red bell pepper, diced
03 1 small yellow onion, diced

Dairy

01 1 cup heavy cream
02 ½ cup freshly grated Parmesan cheese
03 2 tablespoons unsalted butter

Spices & Seasonings

01 1 tablespoon Cajun seasoning
02 ½ teaspoon smoked paprika
03 ½ teaspoon black pepper
04 ½ teaspoon salt, plus more to taste

Oils & Garnish

01 2 tablespoons olive oil
02 2 tablespoons chopped fresh parsley (for garnish)
03 Optional: extra grated Parmesan for serving

How-To

Step 01

Cook tortellini: Bring a large pot of salted water to a boil. Cook tortellini according to package instructions. Drain and set aside.

Step 02

Sauté chicken: Heat 1 tablespoon olive oil in a large skillet over medium-high heat. Add chicken pieces, season with half the Cajun seasoning, salt, and pepper. Sauté until browned and cooked through, about 5-7 minutes. Remove chicken and set aside.

Step 03

Cook vegetables: In the same skillet, add remaining olive oil and butter. Sauté onion and bell pepper for 3-4 minutes until softened. Add garlic and cook for 30 seconds until fragrant.

Step 04

Prepare sauce: Sprinkle remaining Cajun seasoning and smoked paprika into the skillet. Stir, then pour in heavy cream and bring to a gentle simmer, stirring frequently.

Step 05

Melt cheese: Add Parmesan cheese and stir until melted and sauce is smooth. Taste and adjust seasoning if needed.

Step 06

Combine ingredients: Return chicken and cooked tortellini to the skillet. Toss gently to coat everything evenly with sauce.

Step 07

Heat through: Cook for an additional 2-3 minutes until heated through.

Step 08

Garnish and serve: Serve sprinkled with fresh parsley and extra Parmesan if desired.

Essentials

  • Large pot
  • Large skillet
  • Chef's knife
  • Cutting board
  • Wooden spoon or spatula
  • Measuring cups and spoons

Allergy Advisory

Review every component for allergens. Reach out to a health pro if you’re concerned.
  • Contains wheat (tortellini), milk (cream, Parmesan, butter), and possibly eggs (tortellini may contain eggs).

Nutrition Details (per portion)

Facts listed here are for your info, not medical advice. Always double-check if needed.
  • Energy: 620
  • Lipids: 29 g
  • Carbohydrates: 53 g
  • Proteins: 38 g