Southern Cream Parmesan Chicken

Featured in: Comfort Food Sides

This dish features tender, Southern-spiced chicken breasts cooked to golden perfection and combined with pasta tossed in a velvety Parmesan cream sauce. The sauce blends butter, garlic, cream, milk, and cream cheese, enriched with freshly grated Parmesan and brightened by a touch of lemon juice. Seasoned with smoked paprika and cayenne for warmth and layered with garnishes like bacon, green onions, and parsley, this meal offers a comforting fusion of Southern and Italian flavors. It's ready in just 30 minutes, making it a quick yet satisfying dinner option.

Updated on Sun, 23 Nov 2025 09:43:00 GMT
Golden, pan-fried Southern Style Creamy Parmesan Chicken Pasta, with rich sauce and fresh herbs, ready to serve. Save
Golden, pan-fried Southern Style Creamy Parmesan Chicken Pasta, with rich sauce and fresh herbs, ready to serve. | grilto.com

Tender, Southern-spiced chicken crowns rich, silky parmesan cream sauce tossed with pasta for a true comfort classic with Italian flair ready in just 30 minutes.

This creamy parmesan chicken pasta has quickly become a favorite in my household for its rich flavors and ease of preparation.

Ingredients

  • Chicken: 1½ lbs boneless, skinless chicken breasts (pounded to ¾-inch thickness), 2 tsp smoked paprika, 1 tsp garlic powder, 1 tsp onion powder, 1 tsp dried thyme, ½ tsp cayenne pepper (adjust to taste), 1 tsp salt, ½ tsp black pepper, 3 tbsp olive oil
  • Pasta: 12 oz fettuccine or penne pasta
  • Sauce: 4 tbsp butter, 4 cloves garlic minced, ¼ cup all-purpose flour, 2 cups heavy cream, 1 cup whole milk, 1½ cups freshly grated Parmesan cheese, 4 oz cream cheese softened, 2 tbsp fresh lemon juice, 1 tsp Worcestershire sauce
  • Garnish: 2 strips bacon cooked and crumbled (optional), 2 green onions sliced, ¼ cup fresh parsley chopped, Red pepper flakes (to taste), Fresh cracked black pepper (to taste)

Instructions

Step 1:
Place chicken breasts between sheets of plastic wrap and pound to ¾-inch thickness for even cooking.
Step 2:
In a small bowl combine paprika, garlic powder, onion powder, thyme, cayenne, salt, and black pepper.
Step 3:
Season both sides of the chicken thoroughly with the spice mixture.
Step 4:
Heat olive oil in a large skillet over medium-high heat. Cook chicken for 67 minutes per side, until golden brown and cooked through. Transfer to a plate, let rest 5 minutes, then slice into strips. Reserve skillet drippings.
Step 5:
Meanwhile, bring a large pot of salted water to a boil. Cook pasta according to package instructions until al dente. Reserve 1 cup pasta water, then drain.
Step 6:
In a medium saucepan over medium heat, melt butter. Add minced garlic sauté 1 minute. Whisk in flour and cook 2 minutes, stirring constantly, to form a light roux.
Step 7:
Gradually whisk in heavy cream and milk. Add Worcestershire sauce. Simmer, whisking, until slightly thickened (about 34 minutes).
Step 8:
Remove pan from heat. Whisk in cream cheese until fully smooth. Add Parmesan cheese in batches, stirring until melted and sauce is velvety.
Step 9:
Stir in lemon juice. Season with additional salt and pepper to taste. Thin sauce with reserved pasta water as needed for desired consistency.
Step 10:
Toss cooked pasta in the sauce to coat evenly.
Step 11:
Arrange sliced chicken over pasta or mix in. Reheat gently if needed.
Step 12:
Top with bacon (if using), green onions, parsley, red pepper flakes, and extra cracked black pepper. Serve hot with additional Parmesan if desired.
Tender chicken and creamy pasta coated in a luxurious parmesan sauce, a beautiful Southern Style Creamy Parmesan Chicken Pasta. Save
Tender chicken and creamy pasta coated in a luxurious parmesan sauce, a beautiful Southern Style Creamy Parmesan Chicken Pasta. | grilto.com

This recipe always brings the family together for a cozy night filled with laughter and full bellies.

Required Tools

Large skillet, Large pot, Medium saucepan, Meat mallet, Whisk, Tongs, Cheese grater, Colander

Allergen Information

Contains Milk Dairy (cream, milk, Parmesan, cream cheese, butter), Wheat Gluten (pasta, flour). Bacon may contain sulfites. Individuals with allergies should double-check all ingredient labels.

Nutritional Information (per serving)

Calories 545, Total Fat 30 g, Carbohydrates 39 g, Protein 33 g

Savory Southern Style Creamy Parmesan Chicken Pasta, featuring sliced chicken atop perfectly coated pasta, ready for dinner tonight. Save
Savory Southern Style Creamy Parmesan Chicken Pasta, featuring sliced chicken atop perfectly coated pasta, ready for dinner tonight. | grilto.com

This Southern Style Creamy Parmesan Chicken Pasta is a delightful and simple dish that will quickly become a weeknight staple.

Recipe Help & Answers

What type of chicken works best for this dish?

Boneless, skinless chicken breasts pounded to even thickness cook quickly and evenly, ensuring tender slices in the final dish.

How do I achieve a smooth and creamy sauce?

Make a roux with butter and flour, then gradually whisk in cream and milk. Adding cream cheese and Parmesan cheese while off heat prevents curdling for a silky sauce.

Can I adjust the spice level?

Yes, the cayenne pepper amount can be reduced or increased to suit your preferred heat level without overpowering the dish.

What pasta types are suitable for this preparation?

Fettuccine or penne work well, as they hold the creamy sauce effectively and complement the tender chicken slices.

Is there a way to lighten the sauce?

Substituting half-and-half for heavy cream or swapping cream cheese with Greek yogurt can reduce richness while maintaining creaminess.

Why reserve pasta water when draining?

Adding reserved pasta water helps adjust sauce consistency, ensuring it coats the pasta smoothly without becoming too thick or thin.

Southern Cream Parmesan Chicken

Tender Southern-spiced chicken in rich, creamy Parmesan sauce with pasta for a comforting meal ready in 30 minutes.

Prep Time
10 min
Time to Cook
20 min
Complete Time
30 min
From grilto Jake Turner


Skill Level Medium

Cuisine Style Southern Fusion

Serves 4 Portions

Diet Details None specified

What You Need

Chicken

01 1.5 lbs boneless, skinless chicken breasts, pounded to 3/4-inch thickness
02 2 tsp smoked paprika
03 1 tsp garlic powder
04 1 tsp onion powder
05 1 tsp dried thyme
06 1/2 tsp cayenne pepper, adjustable to taste
07 1 tsp salt
08 1/2 tsp black pepper
09 3 tbsp olive oil

Pasta

01 12 oz fettuccine or penne pasta

Sauce

01 4 tbsp unsalted butter
02 4 cloves garlic, minced
03 1/4 cup all-purpose flour
04 2 cups heavy cream
05 1 cup whole milk
06 1.5 cups freshly grated Parmesan cheese
07 4 oz cream cheese, softened
08 2 tbsp fresh lemon juice
09 1 tsp Worcestershire sauce

Garnish

01 2 strips cooked bacon, crumbled (optional)
02 2 green onions, sliced
03 1/4 cup fresh parsley, chopped
04 Red pepper flakes, to taste
05 Fresh cracked black pepper, to taste

How-To

Step 01

Prepare Chicken: Place chicken breasts between plastic wrap sheets and pound to 3/4-inch thickness to ensure even cooking.

Step 02

Season Chicken: Mix smoked paprika, garlic powder, onion powder, thyme, cayenne pepper, salt, and black pepper. Thoroughly coat both sides of chicken breasts with the spice blend.

Step 03

Cook Chicken: Heat olive oil in a large skillet over medium-high heat. Cook chicken for 6 to 7 minutes per side until golden brown and cooked through. Transfer to plate, let rest for 5 minutes, then slice into strips. Reserve skillet drippings.

Step 04

Cook Pasta: Bring a large pot of salted water to a boil. Cook pasta according to package directions until al dente. Reserve 1 cup pasta water and drain pasta.

Step 05

Make Roux: In a medium saucepan over medium heat, melt butter. Add minced garlic and sauté for 1 minute. Whisk in flour and cook for 2 minutes, stirring constantly, forming a light roux.

Step 06

Prepare Sauce Base: Gradually whisk in heavy cream and whole milk. Add Worcestershire sauce and simmer, whisking frequently, until slightly thickened, about 3 to 4 minutes.

Step 07

Incorporate Cheeses: Remove from heat. Whisk in softened cream cheese until smooth. Add Parmesan cheese incrementally, stirring until fully melted and sauce is velvety.

Step 08

Finalize Sauce: Stir in fresh lemon juice. Adjust seasoning with salt and pepper to taste. Thin sauce with reserved pasta water as needed to achieve desired consistency.

Step 09

Combine Pasta and Sauce: Toss cooked pasta in the sauce to coat thoroughly.

Step 10

Serve: Arrange sliced chicken atop pasta or mix in. Reheat gently if necessary. Garnish with bacon (optional), green onions, parsley, red pepper flakes, and fresh cracked black pepper. Serve immediately with additional Parmesan if preferred.

Essentials

  • Large skillet
  • Large pot
  • Medium saucepan
  • Meat mallet
  • Whisk
  • Tongs
  • Cheese grater
  • Colander

Allergy Advisory

Review every component for allergens. Reach out to a health pro if you’re concerned.
  • Contains milk/dairy (cream, milk, Parmesan, cream cheese, butter)
  • Contains wheat/gluten (pasta, flour)
  • Bacon may contain sulfites

Nutrition Details (per portion)

Facts listed here are for your info, not medical advice. Always double-check if needed.
  • Energy: 545
  • Lipids: 30 g
  • Carbohydrates: 39 g
  • Proteins: 33 g